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Friday, 23 May 2014

Crystal chemistry book PDF

Physical Methods in Inorganic Chemistry

First Half: Crystallography

Textbooks

W. Massa/R. Gould: Crystal Structure Determination (Springer)

•

C. Giacovazzo(Ed.): Fundamentals of Crystallography

(Oxford University Press)

•

L. Bragg (Ed.): The Crystalline State (4 volumes)(Cornell University Press)

•

Kleber/Bausch / Bohm: Einführungin die Kristallographie

(VerlagTec)

CLICK HERE TO VIEW / DOWN LOAD THE BOOK

ANALYTICAL INSTRUMENT QUALIFICATION as per USP Gen Chapter

1058 ANALYTICAL INSTRUMENT QUALIFICATION

INTRODUCTION

A large variety of laboratory equipment, instruments, and computerized analytical systems, ranging from simple nitrogen evaporators to complex multiple-function technologies (see Instrument Categories), are used in the pharmaceutical industry to acquire data to help ensure that products are suitable for their intended use. An analyst's objective is to consistently obtain reliable and valid data suitable for the intended purpose. Depending on the applications, users validate their procedures, calibrate their instruments, and perform additional instrument checks, such as system suitability tests and analysis of in-process quality control check samples to help ensure that the acquired data are reliable. With the increasing sophistication and automation of analytical instruments, an increasing demand has been placed on users to qualify their instruments.

Unlike method validation and system suitability activities, analytical instrument qualification (AIQ) currently has no specific guidance or procedures. Competing opinions exist regarding instrument qualification and validation procedures and the roles and responsibilities of those who perform them. Consequently, various approaches have been used for instrument qualification, approaches that require varying amounts of resources and generate widely differing amounts of documentation. This chapter provides a scientific approach to AIQ and considers AIQ as one of the major components required for generating reliable and consistent data. Note that the amount of rigor applied to the qualification process will depend on the complexity and intended use of the instrumentation. This approach emphasizes AIQ's place in the overall process of obtaining reliable data from analytical instruments.

Click here to see 1058 Gen chapter in USPNF

Wednesday, 21 May 2014

Principle of Reversed-Phase Chromatography with animation

Principle of Reversed-Phase Chromatography with animation

Reversed-phase chromatography is all about the particle surface of the HPLC/UPLC column and the eluent solvent. The first slide shows a diagramatic view of the column with many small silica particles

Click here for principle-of-reversed-phase-chromatography-hplcuplc-with-animation/

Monday, 19 May 2014

SOPs FOR ALL DEPARTMENTS

This link is one of the best to create a SOP for any department like production, QC, QA etc.Its providing most information regarding content and template and arrangement of SOP.
Follow this link when you creating new SOP

CLICK HERE

Sunday, 18 May 2014

frequently asked interview questions in phrama interview

01.Q. Which type of tablets are exempted from Disintegration testing?

02.Q.What are the common variables in the manufacturing of tablets?

03. Q. Whether bracketing & validation concept can be applied in process validation?

04. Q. What is the difference between calibration and Validation?

05. Q. WHAT ARE GOOD MANUFACTURING PRACTICES (GMP)?

06.Q. WHO ENFORCES GOOD MANUFACTURING PRACTICES (GMP)?

07.Q.LIST OUT THE APPEARANCE DEFECTS OF TABLES DURING COMPRESSION ACTIVITY ?

08.Q What is the standard number of rotations used for friability test?

09.Q Which capsule is bigger in size - size '0' or size '1'?

And For more questions and Answers

c CLICK HERE pharma-interview-questions